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The processes listed below must occur correctly
for pregnancy to result. The female's reproductive hormone system
involves complex series of relationships controlled primarily by
the hypothalamus gland.
- The female must recruit sufficient follicles under the influence
of FSH. Infertility results when the eggs are "too old"
or loose their capacity to fertilize and develop.
- The egg(s) must grow until it is mature and ready for ovulation.
Failed, or irregular, ovulation is a common cause of infertility.
- A surge of luteinizing hormone causes the egg to be "ovulated"
or released from the follicle.
- During follicular maturation (eggs ripen), the body produces
various hormones, such as estrogen and progesterone that cause
the endometrium (lining of the uterus) to thicken and become
more vascular in order to accept the developing embryo. Infertility
results when the endometrium fails to develop properly, which
may be due to insufficient progesterone.
- Once ovulated, the eggs must travel unimpeded through the
fallopian tubes to the distal end where fertilization occurs.
- The egg must be genetically capable of fertilization and division.
Tubal factor infertility can be caused by scarring from previous
surgery, endometriosis, infection, congenital abnormalities,
and others.
- The fertilized egg (embryo) travels to the lining of the uterus
(endometrium) where it implants and continues cell division.
- The placenta must nourish the developing fetus.
- The fetus must be healthy and the mother must be able to carry
the baby to term.
Dysfunction of the processes outlined above leads to infertility.
Fortunately, today's advanced technologies offer very effective
means to treat most causes of infertility.
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